Welcome to the Macosko Lab
Nervous system biology through innovative genomics
The brain is composed of a remarkably diverse set of cells, many of whose functions have only begun to be explored. We develop new genomics technologies to identify novel cell populations, especially to understand how they contribute to disease states in pathological contexts.
Discovery through new technologies
By harnessing novel experimental and computational methods for single cell profiling, we’ve been able to uncover new cell populations and elucidate previously unknown functions in several regions of the brain. Read more
We develop and deploy cutting-edge molecular techniques to more deeply understand the function of cellular specialization in the nervous system. In particular, we seek clear, actionable explanations for how the cells of the brain go awry in major neuropsychiatric illnesses. Learn more